Superbugs Detection
Since the introduction of antibiotics, the bacteria they treat have been adapting and changing to become more resistant. These antibiotic-resistant bacteria are called superbugs, and they cause serious bacterial infections that are extremely difficult to treat. One of the key challenges in the fight against superbugs is the detection of drug-resistant bacteria. We offer low-cost, rapid detection tools and services for currently known or unknown drug-resistant pathogens.
Different Types of Superbugs
Some of the antibiotic-resistant pathogens that we currently face are classified into different threat levels. Some superbugs are considered to be an urgent threat to us, including Carbapenem-resistant Acinetobacter, Carbapenem-resistant Enterobacteriaceae (CRE), Clostridioides difficile, etc. Pathogens of serious threat level include Multidrug-resistant Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus, etc. Pathogens of concern level include some drug-resistant Streptococcus.
Some superbugs that are common in clinical practice include Carbapenem-resistant Enterobacteriaceae, Methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin-resistant Enterococci (VRE), which can cause a variety of serious infections.
Fig. 1 Different types of common superbugs.
Superbugs Identification Services
For these common superbugs or unknown pathogens, we offer specific identification services among drug-resistant bacteria and identification of unknown pathogens.
- Rapidly identifying the bacteria that cause specific infections is critical to preventing the development of antibiotic resistance. We offer drug-resistant bacteria identification services and development services for specific diagnostic methods. Specific diagnostics can be based on technology platforms such as phage, enzyme assays, biosensors, and CRISPR-Cas systems.
- For some unknown drug-resistant pathogens, we offer genome sequencing services that sequence the entire genome of target bacterium. Genomics can help us determine the source of infection and how drug resistance arises. Genome sequencing can identify the genetic changes that turn bacteria into superbugs. This feasible and cost-effective approach provides a reference for the management and treatment of superbug outbreaks and a range of diseases.
Potential Applications of Our Services
Comprehensive, rapid and reliable detection of drug-resistant bacteria in samples is a key capability in the field of superbug research. Multidrug resistance of pathogenic bacteria is a rapidly developing field with good future prospects in the field of identification and diagnosis based on diverse testing technologies. You can customize our services to develop potential applications in the following areas.
- Development of shorter turnaround time and more sensitive superbug assays for faster and more reliable identification of bacterial diseases
- Typing and bioinformatics studies of drug-resistant pathogens
- Diagnostic development for clinical microbiology laboratories
- Providing valuable information for treatment decisions for bacterial diseases
Multi-drug resistant bacteria are an emerging threat to global health. Rapid and reliable detection is essential to guide treatment and infection control measures. Therefore, identification and diagnostic methods with shorter time to obtain results, high sensitivity and specificity are needed. The need for new technologies is imminent.
Ace Therapeutics' technology meets your bacterial research requirements and can contribute to your drug research efforts. To learn more about applications, please contact us for technical support.